Author/Authors :
Hong، نويسنده , , Bor-Cherng and Chen، نويسنده , , Zhong-Yi and Nagarajan، نويسنده , , Arumugam and Rudresha، نويسنده , , Kottani and Chavan، نويسنده , , Vishal and Chen، نويسنده , , Wei-Hung and Jiang، نويسنده , , Yea-Fen and Zhang، نويسنده , , Shuo-Cang and Lee، نويسنده , , Gene-Hsiang and Sarshar، نويسنده , , Sepehr، نويسنده ,
Abstract :
cis- and trans-2-Substituted-3,6-dihydro-2H-pyran-3-ols have been prepared via an aldol condensation/ring-closing metathesis/enzymatic resolution sequence. The process can be scaled up to yield gram quantities of enantiomerically pure material.
Keywords :
aldol , metathesis , Synthesis , Enzyme , dihydropyran