Title of article :
Total synthesis of pawhuskin C: a directed ortho metalation approach
Author/Authors :
Neighbors، نويسنده , , Jeffrey D. and Salnikova، نويسنده , , Maya S. and Wiemer، نويسنده , , David F.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The total synthesis of the opioid modulator pawhuskin C has been accomplished in eight steps from methyl 3,5-dihydroxybenzoate. The key step in this sequence is a directed ortho metalation reaction conducted without protection of a benzylic alcohol and thus presumed to involve a formal dianion intermediate.
Keywords :
Pawhuskin , Directed ortho metallation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
