Title of article
Total synthesis of (−)-physovenine from (−)-3a-hydroxyfuroindoline
Author/Authors
Sunazuka، نويسنده , , Toshiaki and Yoshida، نويسنده , , Kiminari and Kojima، نويسنده , , Naoto and Shirahata، نويسنده , , Tatsuya and Hirose، نويسنده , , Tomoyasu and Handa، نويسنده , , Masaki and Yamamoto، نويسنده , , Daisuke and Harigaya، نويسنده , , Yoshihiro and Kuwajima، نويسنده , , Isao and ?mura، نويسنده , , Satoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
1459
To page
1461
Abstract
Total synthesis of calabar bean alkaloid (−)-physovenine (−)-3 has been achieved in a concise manner starting from optically active (−)-3a-hydroxyfuroindoline (−)-2, synthesized via modified Sharpless epoxidation of tryptophol 1. Our strategy involved a stereospecific radical substitution reaction and regioselective oxidation at the C5 position.
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844909
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