Title of article
An efficient entry to new sugar modified ketolide antibiotics
Author/Authors
Romero، نويسنده , , Alex and Liang، نويسنده , , Chang-Hsing and Chiu، نويسنده , , Yu-Hung and Yao، نويسنده , , Sulan and Duffield، نويسنده , , Jonathan and Sucheck، نويسنده , , Steven J. and Marby، نويسنده , , Ken and Rabuka، نويسنده , , David and Leung، نويسنده , , Po Yee and Shue، نويسنده , , Youe-Kong and Ichikawa، نويسنده , , Yoshi and Hwang، نويسنده , , Chan-Kou Hwang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
1483
To page
1487
Abstract
A new and efficient route to a ketolide aglycon served as a basis for the unprecedented 5-O-glyco-modification of ketolide antibiotics. Combined with an effective copper-catalyzed triazole-forming reaction a series of novel and potent ketolide antibiotics were synthesized.
Keywords
Ketolide aglycon , glycosylation , Triazole formation , antibiotics
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844920
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