Title of article
Chemoselective reduction of ketones: trifluoromethylketones versus methylketones
Author/Authors
Sasaki، نويسنده , , Shigeru and Yamauchi، نويسنده , , Takayasu and Kubo، نويسنده , , Hajime and Kanai، نويسنده , , Masatomi and Ishii، نويسنده , , Akihiro and Higashiyama، نويسنده , , Kimio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
1497
To page
1500
Abstract
Treatment of an equimolar mixture of trifluoromethylketones (TFMKs) and methylketones (MKs) with Et2Zn resulted in selective reduction of the TFMKs in good yield. In contrast, treatment of an equimolar mixture of TFMKs and MKs with NaBH4 in the presence of CeCl3 in EtOH/H2O (10:1) at −10 °C reduced only the MKs.
Keywords
chemoselective reduction , Trifluoromethylketones , Methylketones , Diethylzinc
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844927
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