Synthesis and in vitro photodynamic activity of novel galactose-containing phthalocyanines
Author/Authors :
Lee، نويسنده , , Priscilla P.S. and Lo، نويسنده , , Pui-Chi and Chan، نويسنده , , Elaine Y.M. and Fong، نويسنده , , Wing-Ping and Ko، نويسنده , , Wing-Hung and Ng، نويسنده , , Dennis K.P. Ng، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
4
From page :
1551
To page :
1554
Abstract :
A novel series of silicon(IV) phthalocyanines with one or two axial acetal-protected galactose substituent(s) have been prepared by typical substitution reactions. The compounds exhibit a high photodynamic activity against HepG2 human hepatocarcinoma cells with IC50 values down to 0.10 μM.
