Title of article
Oxidative cyclization of a seco-cladiellane diterpenoid
Author/Authors
Friedel، نويسنده , , Manuel and Golz، نويسنده , , Gregor and Mayer، نويسنده , , Peter and Lindel، نويسنده , , Thomas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
1623
To page
1626
Abstract
A short and efficient synthesis of a diterpenoid with a 1,2-seco-cladiellane carbon skeleton is described, starting from geraniol and carvone. One-step oxidative cyclization with a RuO2/NaIO4 system leads to two diastereomeric, bicyclic triols, which contain six stereogenic centers and will be helpful in the synthesis of eleutherobin. The stereochemical outcome of this cyclization has been determined by X-ray analysis.
Keywords
Ruthenium tetroxide , 1 , 2-seco-Cladiellane , Sarcodictyins , eleutherobin , oxidative cyclization
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844975
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