Title of article
Novel erythromycin A derivatives: synthesis of 11,12-benzoxazine ketolides
Author/Authors
Zhu، نويسنده , , Bin and Maden، نويسنده , , Amy and Macielag، نويسنده , , Mark J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
1783
To page
1785
Abstract
A novel series of 11,12-benzoxazine ketolide derivatives of erythromycin A has been synthesized. The C11,C12-benzoxazine structure was constructed stereoselectively through an intramolecular Michael addition of a C12-O-(2-aminophenyl) group to the enone functionality of the 10,11-anhydro erythromycin A derivative 3.
Keywords
Benzoxazine , macrolide , Antibacterial , Erythromycin , Ketolide
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845046
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