Title of article
Kinetic resolution of sec-alcohols by a new class of pyridine catalysts having a conformation switch system
Author/Authors
Yamada، نويسنده , , Shinji and Misono، نويسنده , , Tomoko and Iwai، نويسنده , , Yuko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
2239
To page
2242
Abstract
The catalysts having a conformation switch system induced by acylation and deacylation serve as asymmetric acylating catalysts of sec-alcohols. The kinetic resolution of various sec-alcohols resulted in good to excellent selectivities in the presence of 0.5 to 0.05 mol % of catalyst 1a. The conformation switch system plays a key role to attain both good selectivity and high catalytic activity.
Keywords
kinetic resolution , cation–? interaction , Asymmetric acylation , organocatalyst , Conformation switch system
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845214
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