Title of article :
A direct method for the synthesis of nucleoside 5′-methylenebis(phosphonate)s from nucleosides
Author/Authors :
Marcin Kalek، نويسنده , , Marcin and Jemielity، نويسنده , , Jacek and Stepinski، نويسنده , , Janusz and Stolarski، نويسنده , , Ryszard and Darzynkiewicz، نويسنده , , Edward، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
5
From page :
2417
To page :
2421
Abstract :
An efficient method for the preparation of nucleoside 5′-methylenebis(phosphonate)s has been developed. Unprotected nucleosides are phosphonylated directly with methylenebis(phosphonic dichloride). Reaction conditions were optimized to prevent side product formation.
Keywords :
nucleosides , bisphosphonates , Nucleotides , Synthesis
Journal title :
Tetrahedron Letters
Serial Year :
2005
Journal title :
Tetrahedron Letters
Record number :
1845282
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1845282
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