Title of article :
Synthesis of chiral N-protected 1,2-dihydro-quinoline-2-carbonitrile and 1,2-dihydro-isoquinoline-1-carbonitrile via an asymmetric Reissert reaction
Author/Authors :
Pauvert، نويسنده , , Mickaël and Collet، نويسنده , , Sylvain C. and Bertrand، نويسنده , , Marie-Jo and Guingant، نويسنده , , André Y. and Evain، نويسنده , , Michel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Addition of cyanide ion to chiral N-acyl-quinolinium and N-acyl-isoquinolinium salts led selectively to 1,2-addition products. Removal of the chiral auxiliary affords the title compounds in pure enantiomeric form.
Keywords :
2-dihydro-isoquinoline-1-carbonitrile , N-protected 1 , 2-dihydro-quinoline-2-carbonitrile , Chiral oxazolidinone-derived auxiliary , N-protected 1 , Asymmetric Reissert reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
