Author/Authors :
Yang، نويسنده , , Hui-Min and Lai، نويسنده , , Chi K. and Gjertson، نويسنده , , David W. and Baruch-Oren، نويسنده , , Tamar and Ra، نويسنده , , Seong H. and Watts، نويسنده , , William and Wallace، نويسنده , , William D. and Shintaku، نويسنده , , Peter and Kobashigawa، نويسنده , , Jon A. and Fishbein، نويسنده , , Michael C.، نويسنده ,
Abstract :
We compared the interobserver reproducibility of the 1990 and 2004 International Society for Heart and Lung Transplantation (ISHLT) grading system for cardiac rejection. The 2004 ISHLT grading system for cardiac allograft rejection did not improve reproducibility partly due to pathologistsʹ disagreement in diagnosing Grades 1B/1R and 3A/2R rejection. To achieve better reproducibility, better criteria for defining 1B/1R vs. 3A/2R rejection and markers of myocyte injury are needed.
Keywords :
endomyocardial biopsy , Acute cellular rejection , Grading , Cardiac transplant rejection , Interobserver reproducibility , 2004 ISHLT scale
