Title of article
Enantioselective reactions of tert-butyl glycinate–benzophenone Schiff base catalyzed by chiral phase-transfer catalyst in aqueous media without any organic solvent
Author/Authors
Mase، نويسنده , , Nobuyuki and Ohno، نويسنده , , Takahiro and Morimoto، نويسنده , , Hironao and Nitta، نويسنده , , Fumito and Yoda، نويسنده , , Hidemi and Takabe، نويسنده , , Kunihiko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3213
To page
3216
Abstract
Chiral phase-transfer catalyzed enantioselective alkylations of tert-butyl glycinate–benzophenone Schiff base were investigated in aqueous media without any organic solvent. Reactions in aqueous media smoothly proceeded to give the desired product in higher yield than under standard liquid–liquid biphasic conditions. In aqueous media the formation of benzophenone, which was caused by in situ hydrolysis of Schiff base, was depressed.
Keywords
Chiral phase-transfer catalyst , asymmetric synthesis , aqueous media
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845555
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