Title of article :
Synthesis and derivatisation of N,N′-trisubstituted 1,2-diamines derived from (1R,2R)-1,2-diaminocyclohexane
Author/Authors :
Boyd، نويسنده , , Ewan and Coumbarides، نويسنده , , Gregory S. and Eames، نويسنده , , Jason R. Jones، نويسنده , , Ray V.H. and Stenson، نويسنده , , Rachel A. and Suggate، نويسنده , , Michael J.، نويسنده ,
Abstract :
The synthesis of N,N′-trisubstituted 1,2-diamines can be achieved by simple reduction of an aminal derived from (1R,2R)-diaminocyclohexane. We comment on the scope and limitation of this reduction and discuss its application towards the synthesis of unsymmetrical N,N′-tetrasubstituted 1,2-diamines.
