Title of article
Chiral 5-(diphenylphosphanyl)-1,2,3,4-tetrahydroacridines: new N,P-ligands for asymmetric catalysis
Author/Authors
Giorgio Chelucci، نويسنده , , Giorgio and Orrù، نويسنده , , Gianmauro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3493
To page
3496
Abstract
Three chiral 5-(diphenylphosphanyl)-1,2,3,4-tetrahydroacridines, as first representative examples of a new class of chiral N,P-ligands were prepared from (+)-nopinone, (+)-camphor and 5α-androst-2-en-17-one. These ligands have been assessed in the enantioselective palladium-catalysed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimethyl malonate. Enantioselectivity up to 74% has been obtained.
Keywords
Palladium catalysts , Enantioselective allylic substitutions , Phosphinopyridine ligands , Chiral acridines
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845649
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