Title of article :
Tandem Michael addition and intramolecular aldol cyclization of 1,2-dideoxy-1-nitroheptitols derived from sugars
Author/Authors :
Berrocal، نويسنده , , M.V. and Gil، نويسنده , , M.V and Romلn، نويسنده , , E. and Serrano، نويسنده , , J.A. and Hursthouse، نويسنده , , M.B. and Light، نويسنده , , M.E.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The base-catalyzed Michael addition of primary nitro compounds derived from sugars with 2 equiv of methyl vinyl ketone or acrolein was followed, in situ, by an asymmetric intramolecular aldol cyclization, thus yielding 2-acyl-4-glyco-4-nitrocyclohexanol derivatives with high diastereoselectivity.
Keywords :
Michael addition , Aldol cyclization , Nitro compounds , Sugars
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
