Title of article
[Ru(DMSO)4]Cl2 catalyzes the α-alkylation of ketones by alcohols
Author/Authors
Martيnez، نويسنده , , Ricardo and Brand، نويسنده , , Gabriel J. and Ramَn، نويسنده , , Diego J. and Yus، نويسنده , , Miguel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3683
To page
3686
Abstract
The electrophilic α-alkylation of ketones with alcohols was accomplished by a [Ru(DMSO)4]Cl2 catalyzed process, water being the only wasted material. The reaction can be successfully governed to produce either the expected ketones or their related alcohols only by changing the reaction conditions. When 2-aminobenzyl alcohol was used, a cyclization process took place to yield 2,3-disubstituted quinolines.
Keywords
C–C bond forming , Alkylation , Ruthenium catalysis , ketones , Quinolines
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845732
Link To Document