Title of article
Skeletal rearrangements of bicyclo[2.2.2]lactones: a short and efficient route towards Corey’s lactone
Author/Authors
Augustyns، نويسنده , , Beno?ˆt and Maulide، نويسنده , , Nuno and Mark?، نويسنده , , Istv?n E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
3895
To page
3899
Abstract
The application of a unique tandem radical-initiated, Brönsted acid-catalysed, skeletal rearrangement of bicyclo[2.2.2]lactones provides a novel route towards Corey’s lactone 2. The strategy also features a high-pressure promoted inverse electron-demand Diels–Alder (IEDDA) reaction of 3-carbomethoxy-2-pyrone (3-CMP), which proceeds with complete regio- and diastereocontrol.
Keywords
bicyclic , Lactones , radical , Corey’s lactone , 3-CMP , Diels–Alder , Rearrangement
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845819
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