Title of article :
2-α-Hydroxybenzhydryl- and 2,7-di(α-hydroxybenzhydryl)-1,8-bis(dimethylamino)naphthalenes: the first examples of stabilization of in/out proton sponge conformers by intramolecular hydrogen bonding. The most flattened amino group ever participating in IHB
Author/Authors :
Pozharskii، نويسنده , , Alexander F. and Ryabtsova، نويسنده , , Oksana V. and Ozeryanskii، نويسنده , , Valery A. and Degtyarev، نويسنده , , Alexander V. and Starikova، نويسنده , , Zoya A. and Sobczyk، نويسنده , , Lucjan and Filarowski، نويسنده , , Alexander، نويسنده ,
Abstract :
2-(α-Hydroxybenzhydryl)- 6 and 2,7-di(α-hydroxybenzhydryl)-1,8-bis(dimethylamino)naphthalenes 8 have been shown to exist in crystals as in/out conformers stabilized by O–H⋯N intramolecular hydrogen bonding. In agreement with X-ray studies, the NMR data are also consistent with 7 retaining its in/out form in solution, whilst for 8 superimposed equilibrating in/out–out/in conformers are observed.
