Title of article
The ‘fully protected backbone’ approach as a versatile tool for a new solid-phase PNA synthesis strategy
Author/Authors
Gregory Upert، نويسنده , , Gregory and Mehiri، نويسنده , , Mohamed and Goddard، نويسنده , , Mary-Lorène and Giorgio، نويسنده , , Audrey Di and Benhida، نويسنده , , Rachid and Condom، نويسنده , , Roger and Patino، نويسنده , , Nadia، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
4081
To page
4085
Abstract
The ‘fully protected backbone’ (FPB) strategy has been efficiently adapted to the solid-phase synthesis of homothymine, homocytosine and ‘mixed’ pyrimidine PNAs. This versatile and simple method avoids the preparation of PNA monomers and relies on easy available starting materials, highly efficient backbone elongations and effective nucleobase units condensations.
Keywords
solid-phase synthesis , PNA , FPB strategy
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845893
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