Title of article
N-Methylpyrrolidin-2-one hydrotribromide (MPHT) a mild reagent for selective bromination of carbonyl compounds: synthesis of substituted 2-bromo-1-naphtols
Author/Authors
Bekaert، نويسنده , , Alain and Provot، نويسنده , , Olivier and Rasolojaona، نويسنده , , Olimihamina and Alami، نويسنده , , Mouâd and Brion، نويسنده , , Jean-Daniel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
4187
To page
4191
Abstract
The reaction of the N-methylpyrrolidin-2-one hydrotribromide complex (MPHT) with substituted-1-tetralones has been investigated. This safety reagent proved to be successful for selective α,α-dibromination of tetralones. Moreover, under base-free conditions, several 2-bromo-1-naphtols were obtained from tetralones in a ‘one pot’ sequence in good to excellent yields.
Keywords
Halogenation , MPHT , 1-Tetralones , 2-Bromo-1-naphtols
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845930
Link To Document