Title of article
First regiospecific, enantiospecific total synthesis of gardnerine and gardnutine
Author/Authors
Zhou، نويسنده , , Hao and Han، نويسنده , , Dongmei and Liao، نويسنده , , Xuebin and Cook، نويسنده , , James M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
6
From page
4219
To page
4224
Abstract
The first enantiospecific total synthesis of gardnerine and gardnutine has been achieved from 6-methoxy-d-tryptophan via the asymmetric Pictet–Spengler reaction, a stereocontrolled intramolecular enolate driven palladium-mediated cross-coupling reaction and a chemospecific, regiospecific hydroboration/oxidation sequence as key steps.
Keywords
Pictet–Spengler reaction , Intramolecular enolate driven palladium-mediated cross-coupling , Hydroboration
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845940
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