Title of article
Synthesis of C(1)–C(11) oxygen-bridged pregnanes
Author/Authors
Veleiro، نويسنده , , Adriana S. and Taich، نويسنده , , Paula J. and Alvarez، نويسنده , , Lautaro D. and Di Chenna، نويسنده , , Pablo H. and Burton، نويسنده , , Gerardo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
4235
To page
4238
Abstract
A general procedure for the synthesis of 1α,11α- and 1β,11α-epoxysteroids is described, using an intramolecular remote functionalization reaction involving the photolysis of 11α-hydroxysteroids in the presence of diacetoxyiodobenzene and iodine. Three 1,11-epoxypregnanes were prepared, two of them (compounds 10 and 14) are conformationally constrained analogues of steroidal hormones, compound 13 is a synthetic precursor of neurosteroids.
Keywords
1 , 11-Epoxypregnane , Remote functionalization reaction , DIB , Diacetoxyiodobenzene , Steroid
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845945
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