Title of article
Solvent-free biocatalytic amidation of carboxylic acids
Author/Authors
Prasad، نويسنده , , Ashok K. and Husain، نويسنده , , Mofazzal and Singh، نويسنده , , Brajendra K. and Gupta، نويسنده , , Rajinder K. and Manchanda، نويسنده , , Vijay K. and Olsen، نويسنده , , Carl E. and Parmar، نويسنده , , Virinder S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
4511
To page
4514
Abstract
Lipase-catalyzed enantioselective amidation was performed by reacting the racemic amine with aliphatic acids in nonsolvent system. The reaction equilibrium was shifted towards amide synthesis by the removal of water under reduced pressure. This methodology avoids the use of activating agents and hazardous solvents.
Keywords
enantioselective , Lipase , Amidation , Bulk reaction , Chiral amide
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846042
Link To Document