Title of article
Kinetic resolution by copper-catalyzed azide–alkyne cycloaddition
Author/Authors
Meng، نويسنده , , Jun-cai and Fokin، نويسنده , , Valery V. and Finn، نويسنده , , M.G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
4543
To page
4546
Abstract
The use of chiral pybox ligands imparts enantioselectivity to the CuI-catalyzed azide–alkyne cycloaddition reaction, in the form of kinetic resolution of α-chiral azides and desymmetrization of gem-diazides. While levels of selectivity are modest, the results show unequivocally that the process benefits from ligand-accelerated catalysis.
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846050
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