Title of article
Iodine as a novel and efficient reagent for the synthesis of α-aminonitriles by a three-component condensation of carbonyl compounds, amines, and trimethylsilyl cyanide
Author/Authors
Royer، نويسنده , , Laurel and De، نويسنده , , Surya K. and Gibbs، نويسنده , , Richard A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
4595
To page
4597
Abstract
A straightforward and general method has been developed for the synthesis of α-aminonitriles by simply combining aldehydes or ketones, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of molecular iodine at room temperature.
Keywords
Aldehydes , ketones , Amines , Trimethylsilyl cyanide , ?-aminonitriles , iodine
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846068
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