Title of article
An efficacious method for the halogenation of β-dicarbonyl compounds under mildly acidic conditions
Author/Authors
Matthew L. Meketa، نويسنده , , Matthew L. and Mahajan، نويسنده , , Yogesh R. and Weinreb، نويسنده , , Steven M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
4749
To page
4751
Abstract
A variety of 1,3-diketones, β-ketoesters and malonates can be chlorinated in high yields using sodium hypochlorite in a 5:2 mixture of acetone/acetic acid at 0 °C for 1 h. Similarly, bromination of these dicarbonyl substrates can be accomplished under the same conditions using sodium hypobromite.
Keywords
3-diketones , Malonates , ?-Ketoesters , Chlorination , Bromination , Vinyl chlorides , 1
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846119
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