Title of article
A simpler and greener protocol for the preparation of β-acetylamino ketones by a one-pot reaction of aryl aldehydes, enolisable ketones, acetyl chloride and acetonitrile in the presence of zeolite Hβ as a reusable catalyst
Author/Authors
Bhat، نويسنده , , Ramakrishna P. and Raje، نويسنده , , Vivek P. and Alexander، نويسنده , , Varughese M. and Patil، نويسنده , , Sachin B. and Samant، نويسنده , , Shriniwas D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
4801
To page
4803
Abstract
β-Acetylamino ketones have been obtained in a one-pot coupling of an aldehyde with an enolisable ketone, acetyl chloride and acetonitrile in the presence of zeolite Hβ as catalyst at room temperature (26–28 °C). The procedure has the advantages of mild workup, circumvention of high temperature and inert atmosphere. The catalyst was found to be recyclable.
Keywords
one-pot synthesis , ?-Acetylamino ketones , multicomponent reaction , H? catalyst
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846139
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