Title of article
Penicillones A and B, two novel polyketides with tricyclo [5.3.1.03,8] undecane skeleton, from a marine-derived fungus Penicillium terrestre
Author/Authors
Liu، نويسنده , , Weizhong and Gu، نويسنده , , Qianqun and Zhu، نويسنده , , Weiming and Cui، نويسنده , , Chengbin and Fan، نويسنده , , Guotao and Zhu، نويسنده , , Tianjiao and Liu، نويسنده , , Hongbing and Fang، نويسنده , , Yuchun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
4993
To page
4996
Abstract
Two novel polyketides, penicillones A (1) and B (2), with tricyclo [5.3.1.03,8] undecane skeleton, were isolated from Penicillium terrestre. Their structures and relative stereochemistries were determined on the basis of spectroscopic methods. The absolute configuration of 2 was established by the modified Mosher’s method, while that of 1 was deduced from the similar CD absorptions of 1 and 2. Compound 1 showed weak cytotoxicities against P338 and A-549 cell lines, while 2 was inactive against P388.
Keywords
microorganism , Fungus , Penicillium terrestre , Polyketide , 8] undecane , Penicillone
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846204
Link To Document