Author/Authors :
Simone، نويسنده , , Michela Iezzi and Soengas، نويسنده , , Raquel and Newton، نويسنده , , Christopher R. and Watkin، نويسنده , , David J. and Fleet، نويسنده , , George W.J.، نويسنده ,
Abstract :
Efficient SN2 ring closure of open chain trihydroxytriflates—in which the leaving group is on a primary carbon adjacent to a quaternary centre—provides access to tetrahydrofurans with branched carbon chains from branched carbohydrate lactones; the first examples of a new class of branched chain tetrahydrofuran α,α-disubstituted-δ-sugar amino acid scaffolds are described.
