Title of article
Oxazoline as a useful tool in organic synthesis: preparation of 4-aryl-1,2,3,4-tetrahydroisoquinoline alkaloid skeleton
Author/Authors
Seijas، نويسنده , , Julio A. and Vلzquez-Tato، نويسنده , , M. Pilar and Martيnez، نويسنده , , M. Montserrat and Pizzolatti، نويسنده , , Moacir G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
5827
To page
5830
Abstract
New direct strategy for the synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines. The key steps are based on oxazoline chemistry: nucleophilic substitution in an ortho-methoxyphenyloxazoline with a Grignard reagent and a 1,6-conjugate addition of a lithium amide to o-styrylphenyloxazoline.
Keywords
4-Tetrahydroisoquinoline , 1 , 2-Oxazoline , 6-Conjugate addition , 4-aryl-1 , 2 , 3
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846504
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