Title of article :
A mild and efficient method for halogenation of 3,5-dimethyl pyrazoles by ultrasound irradiation using N-halosuccinimides
Author/Authors :
Stefani، نويسنده , , Hélio A. and Pereira، نويسنده , , Claudio M.P. and Almeida، نويسنده , , Roberta B. and Braga، نويسنده , , Rodolpho C. and Guzen، نويسنده , , Karla P. and Cella، نويسنده , , Rodrigo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The 4-halo-3,5-dimethyl pyrazoles have been synthetisized in good yields in short reaction times in the absence of a catalyst by reaction of 3,5-dimethyl pyrazoles with N-halosuccinimides (NBS, NCS and NIS) under ultrasound irradiation. Finally, the halogenation of pyrazoles with Br2, ICl and I2 was showed in similar conditions.
Keywords :
Heterocycles , pyrazoles , Halogenation , Ultrasound irradiation , N-Halosuccinimides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
