Efficient fluoride-mediated synthesis of 5-alkyl amino- and ether-substituted pyrazoles
Author/Authors :
Andrei Shavnya، نويسنده , , Andrei and Sakya، نويسنده , , Subas M. and Minich، نويسنده , , Martha L. and Rast، نويسنده , , Bryson and Lundy DeMello، نويسنده , , Kristin and Jaynes، نويسنده , , Burton H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
5
From page :
6887
To page :
6891
Abstract :
Fluoride-mediated nucleophilic substitution reactions of 1-(4-methylsulfonyl (or sulfonamido)-2-pyridyl)-5-chloro-4-cyano pyrazoles with various amines and alcohols occur under mild conditions to provide the 5-alkyl amino and ether pyrazoles in moderate to high yields.
