Title of article
Synthesis of Fmoc-protected aza-β3-amino acids via reductive amination of glyoxylic acid
Author/Authors
Busnel، نويسنده , , Olivier and Bi، نويسنده , , Lanrong and Baudy-Floc’h، نويسنده , , Michèle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
7073
To page
7075
Abstract
The reductive amination of glyoxylic acid, with a protected Fmoc hydrazine, has been developed as a simple and efficient method for the preparation of Fmoc-aza-β3-amino acid residues (aza-β3-aa). Anchoring on resin of these residues will be described as well as the synthesis of hybrid peptide.
Keywords
Aza-?3-amino acid , Fmoc protecting group , Peptidomimetics , Loading resin , reductive amination
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846885
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