Application of AM SURE™ resin to solid-phase peptide synthesis

A core-shell structure was found in AM SURE™ resin, in which most amino groups were located at the skin layer. The AM SURE™ resin revealed better synthetic efficiency, compared to the noncore-shell type resin in the synthesis of the fragment 65–74 of acyl carrier protein, the fragment 27–35 of HIV (human immunodeficiency virus) fusion inhibitor (T-20) and the Jung–Redemann 10-mer.