Title of article
Barbier allylation–Prins reaction of PEG-bound aldehydes—soluble polymer-supported synthesis of 2,4,6-trisubstituted tetrahydropyrans
Author/Authors
Sampath Kumar، نويسنده , , H.M. and Qazi، نويسنده , , Naveed Ahmed and Shafi، نويسنده , , Syed and Naveen Kumar، نويسنده , , V. and Krishna، نويسنده , , A.D. and Yadav، نويسنده , , J.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
7205
To page
7207
Abstract
PEG-bound aldehydes undergo zinc-mediated Barbier allylation to form homoallylic alcohols, which on further reaction with various aldehydes in the presence of BF3·Et2O through a Prins cyclization afford 4-hydroxytetrahydropyrans and 4-fluorotetrahydropyrans.
Keywords
PEG , Prins cyclization , Barbier allylation , tetrahydropyran
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846936
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