Title of article :
A stereoselective route to cis-2-phenyl-3-piperidinol
Author/Authors :
Liang، نويسنده , , Ningning and Srinivas، نويسنده , , Pusuluri and Datta، نويسنده , , Apurba، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Enantiopure cis-2-phenyl-3-piperidinol is a commonly used synthon for the obtention of a potent class of neurokinin substance P receptor antagonists. Starting from (R)-phenylglycine, the present report describes an efficient route for the stereoselective synthesis of the above piperidinol structural core.
Keywords :
Piperidine , stereoselective , Phenylglycine , bioactive , Chelation controlled
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
