Title of article :
A convenient synthesis of (E)-α-alkylidene-γ-lactams and (E)-3-alkylideneoxindoles by rhodium-catalyzed intramolecular hydroamidation
Author/Authors :
Kobayashi، نويسنده , , Yusuke and Kamisaki، نويسنده , , Haruhi and Yanada، نويسنده , , Kazuo and Yanada، نويسنده , , Reiko and Takemoto، نويسنده , , Yoshiji، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Rhodium-catalyzed carbonylative cyclization without carbon monoxide was investigated. Cyclization of various formamides having alkynyl groups proceeded smoothly in the presence of Rh4(CO)12 to provide α-alkylidene-γ-lactams or 3-alkylideneoxindoles in moderate to good yields with high (E)-selectivity.
Keywords :
Rhodium catalyst , Carbonylative cyclization , C–H activation , formamides , Hydroamidation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
