Title of article
Synthesis and properties of purine-type base-discriminating fluorescent (BDF) nucleosides: distinction of thymine by fluorescence-labeled deoxyadenosine derivatives
Author/Authors
Saito، نويسنده , , Yoshio and Hanawa، نويسنده , , Kazuo and Motegi، نويسنده , , Kaori and Omoto، نويسنده , , Kenji and Okamoto، نويسنده , , Akimitsu and Saito، نويسنده , , Isao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
7605
To page
7608
Abstract
Novel base-discriminating fluorescent (BDF) nucleoside, 8-fluorescence-labeled adenosine derivative (8PyA), was developed for the detection of thymine base on a target DNA. The BDF nucleoside was incorporated into oligodeoxynucleotides by post-synthetic modification. BDF probes containing 8PyA selectively emit fluorescence only when the base opposite BDF nucleoside is thymine and act as effective reporter probes for homogeneous SNP typing.
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847133
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