Title of article
A facile synthesis of antitumoral indeno[1,2-c]pyrazole-4-one by mild oxidation with molecular oxygen
Author/Authors
Tao، نويسنده , , Zhi-Fu and Sowin، نويسنده , , Thomas J. and Lin، نويسنده , , Nan-Horng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
7615
To page
7618
Abstract
An efficient, convenient, and general synthetic method for indeno[1,2-c]pyrazole-4-ones through oxidation of indenopyrazoles by treatment with a base and molecular oxygen is described, and a possible mechanism for the oxidation is proposed. The product indeno[1,2-c]pyrazole-4-ones were elaborated further by Suzuki coupling and Mitsunobu reaction.
Keywords
Pyrazoloindenone , Molecular oxygen , Suzuki coupling , Mitsunobu reaction , Antitumor activity , Indenopyrazole , Oxidation
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847137
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