Title of article :
Expedient synthesis of substituted imidazoles from nitriles
Author/Authors :
Frutos، نويسنده , , Rogelio P. and Gallou، نويسنده , , Isabelle and Reeves، نويسنده , , Diana and Xu، نويسنده , , Yibo and Krishnamurthy، نويسنده , , Dhileepkumar and Senanayake، نويسنده , , Chris H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Expedient and practical new methodology for the synthesis of substituted imidazoles was developed to provide a rapid access to a variety of 2-substituted, 1,2-disubstituted and 1,2,4-trisubstituted imidazoles by the direct CuCl-mediated reaction of nitriles with α-amino acetals in an intermolecular as well as intramolecular fashion.
Keywords :
Heterocycles , Copper-mediated , substituted imidazoles , ?-Amino acetals , Nitriles
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
