Title of article
A new route to 3,4-disubstituted piperidines: formal synthesis of (−)-paroxetine and (+)-femoxetine
Author/Authors
Yamada، نويسنده , , Shinji and Jahan، نويسنده , , Ishrat، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
8673
To page
8676
Abstract
A new route to 3,4-disubstituted piperidines was developed using chiral 1,4-dihydropyridines as key intermediates, the synthetic utility of which was demonstrated by formal synthesis of (−)-paroxetine and (+)-femoxetine.
Keywords
1 , 4-dihydropyridine , (?)-Paroxetine , (+)-Femoxetine , face-selective addition , cation–? interaction
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847833
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