• Title of article

    A new route to 3,4-disubstituted piperidines: formal synthesis of (−)-paroxetine and (+)-femoxetine

  • Author/Authors

    Yamada، نويسنده , , Shinji and Jahan، نويسنده , , Ishrat، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    8673
  • To page
    8676
  • Abstract
    A new route to 3,4-disubstituted piperidines was developed using chiral 1,4-dihydropyridines as key intermediates, the synthetic utility of which was demonstrated by formal synthesis of (−)-paroxetine and (+)-femoxetine.
  • Keywords
    1 , 4-dihydropyridine , (?)-Paroxetine , (+)-Femoxetine , face-selective addition , cation–? interaction
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2005
  • Journal title
    Tetrahedron Letters
  • Record number

    1847833