Author/Authors :
Liav، نويسنده , , Avraham and Huang، نويسنده , , Hairong and Ciepichal، نويسنده , , Ewa and Brennan، نويسنده , , Patrick J. and McNeil، نويسنده , , Michael R.، نويسنده ,
Abstract :
Decaprenylphosphoryl β-d-arabinofuranose (DPA) is known to be a key arabinose donor in mycobacteria. In order to study the biosynthesis of the major polysaccharides from the mycobacterial cell wall, it was necessary to develop a practical and stereoselective synthetic scheme for DPA. This goal was achieved by coupling of a suitably protected β-d-arabinofuranosyl phosphate intermediate with an activated form of decaprenol and subsequent deprotection.
