Title of article
A facile one-pot synthesis of 8-oxo-7,8-dihydro-(2′-deoxy)adenosine in water
Author/Authors
Chatgilialoglu، نويسنده , , Chryssostomos and Navacchia، نويسنده , , Maria Luisa and Postigo، نويسنده , , Al، نويسنده ,
Issue Information
دوماهنامه با شماره پیاپی سال 2006
Pages
4
From page
711
To page
714
Abstract
Reaction of 2-mercaptoethanol with 8-bromo-2′-deoxyadenosine and 8-bromo-adenosine in aqueous solution and in the presence of triethylamine gave the 8-oxo-adenine derivatives in very good yields. Some mechanistic details are reported.
Keywords
DNA damage , nucleosides , 8-Oxo-7 , 8-dihydro-2?-deoxyadenosine , Mercaptoethanol , 8-Bromo-2?-deoxyadenosine
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1848580
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