Title of article :
Synthesis of imidazole phosphinic acids as I4AA analogues
Author/Authors :
Orain، نويسنده , , David and Mattes، نويسنده , , Henri، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The GABAC receptor has been identified as a potentially attractive target involved in a number of eye diseases. TPMPA is the best antagonist reported so far. The synthesis of two new pharmacophores based on imidazole phosphinic acid core structure will be presented.
Keywords :
GABA , TPMPA , Phosphinic acid , Imidazole
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters