The synthesis of indanones related to combretastatin A-4 via microwave-assisted Nazarov cyclization of chalcones
Author/Authors :
Lawrence، نويسنده , , Nicholas J. and Armitage، نويسنده , , E. Simon M. and Greedy، نويسنده , , Benjamin and Cook، نويسنده , , Darren and Ducki، نويسنده , , Sylvie and McGown، نويسنده , , Alan T.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Pages :
4
From page :
1637
To page :
1640
Abstract :
A fast and efficient microwave-assisted synthesis of combretastatin A-4-like indanones has been developed. Microwave irradiation provides a useful alternative to traditional heating techniques to promote the TFA-catalyzed Nazarov cyclization of chalcones.