Title of article
Efficient preparation of chiral diamines via Red-Al reduction of N-Boc-protected amino acid-derived secondary amides
Author/Authors
Voight، نويسنده , , Eric A. and Bodenstein، نويسنده , , Matthew S. and Ikemoto، نويسنده , , Norihiro and Kress، نويسنده , , Michael H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
1717
To page
1720
Abstract
Conditions have been developed for the selective reduction of N-Boc-protected amino acid-derived secondary amides, avoiding the formation of overreduction and cyclic urea byproducts. The method is showcased by the efficient formal synthesis of NK-1 antagonist LY303870.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849162
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