Title of article
Diastereoselective synthesis of β-aminocyclopentene sulfonic acid via hetero Diels–Alder reaction
Author/Authors
Fusi، نويسنده , , Stefania and Papandrea، نويسنده , , Giovanni and Ponticelli، نويسنده , , Fabio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
1749
To page
1752
Abstract
A new cyclopentene GABA analogue was synthesized as a conformationally rigid analogue of the epilepsy drug vigabatrin. N-Sulfinyl dienophile Diels–Alder methodology, followed by alkaline hydrolysis of the corresponding dihydrothiazine oxide, oxidation and deprotection of the amino group gave cis-4-aminocyclopent-2-ene-1-sulfonic acid. The corresponding N,N-dimethylsulfinamide was also obtained.
Keywords
Performic acid , N-Sulfinyl dienophile Diels–Alder methodology , Aminocyclopentene sulfonic acid , GABA-AT
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849181
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