Title of article
Bromine–magnesium exchange of 5-bromo-2-picoline via an organomagnesium complex nBu2iPrMgLi: a new preparation methodology of functionalized picolines under noncryogenic conditions
Author/Authors
Kii، نويسنده , , Satoshi and Akao، نويسنده , , Atsushi and Iida، نويسنده , , Takehiko and Mase، نويسنده , , Toshiaki and Yasuda، نويسنده , , Nobuyoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
1877
To page
1879
Abstract
The organomagnesium complex nBu2iPrMgLi, readily prepared from nBuLi and iPrMgCl (2:1), is quite efficient for the bromine–magnesium exchange of 5-bromo-2-picoline under noncryogenic conditions (at −10 °C). The resulting picolylmagnesium complex reacts with various electrophiles to afford functionalized picolines.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849227
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