Title of article
Microwave promoted rapid nitration of phenolic compounds with calcium nitrate
Author/Authors
Bose، نويسنده , , Ajay K. and Ganguly، نويسنده , , Subhendu N. and Manhas، نويسنده , , Maghar S. and Rao، نويسنده , , Sheetal and Speck، نويسنده , , Jeffrey and Pekelny، نويسنده , , Uri and Pombo-Villars، نويسنده , , Esteban، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
1885
To page
1888
Abstract
Highly accelerated and safe nitration of phenolic compounds has been found to be feasible with a mixture of calcium nitrate and acetic acid as an efficient nitration agent under brief microwave irradiation. This method is compatible with the green chemistry approach because calcium salts—the inorganic byproducts—can be useful agrochemicals rather than waste chemicals. Commercially available 15N-labeled calcium nitrate is convenient for the preparation of 15N-labeled compounds for metabolic studies and mass spectrometry. This safe nitration method can be included in laboratory experiments for high school and college students.
Keywords
Microwave-assisted nitration , Green chemistry approach , Mononitro phenol , Calcium nitrate for nitration , 15N-labeled compounds
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849231
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